Antioxidant Activity of Jojoba (Simmondsia chinensis) Seed Residue Extract

Arnold Patogi Siahaan(1), Eti Rohaeti(2), Ali Mahmoud Muddathir(3), Irmanida Batubara(4),


(1) Department of Chemistry, Faculty of Mathematics and Natural Science, IPB University
(2) Department of Chemistry, Faculty of Mathematics and Natural Science, IPB University, Indonesia
(3) Department of Horticulture, Faculty of Agriculture, University of Khartoum, Sudan
(4) Department of Chemistry, Faculty of Mathematics and Natural Science, IPB University

Abstract

Jojoba (Simmondsia chinensis (Link)) is a shrub plant that widely used as cosmetic ingredients especially jojoba oil. When making jojoba oil, the residue still reminds and become waste. This study aimed to determine the antioxidant activity of jojoba seed residue (JSR). Jojoba seed residue was collected from Sudan. The JSR extracted by maceration with n-hexane, ethyl acetate, and 70% ethanol solvent. The antioxidant activity was determined using DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. The result showed that 70% ethanol extract of JSR had the highest antioxidant activity with 50% Inhibition Concentration (IC50) value of 219.42 mg/L. The 70% ethanol extract was fractionated by using silica gel column chromatography with gradient elution produced 10 fractions. All fractions showed antioxidant activity (IC50106-447 mg/L). Fraction 3 had the highest antioxidant activity with IC50 value of 106.26 mg/L. Therefore, JSR has a great potential for use as a raw material in cosmetic and pharmaceutical products industry, or as a source of bioactive compounds.

Keywords

Simmondsia chinensis; Seed residue; Antioxidant; DPPH; Bioautography

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References

Abbott, T. P., Holser, R. A., Plattner, B. J., Plattner, R. D., & Purcell, H. C. (1999). Pilot-scale isolation of simmondsin and related jojoba constituents. Industrial Crops and Products, 10, 65-72.

Abbassy, M., Abdelgaleil, S., Belal, A., & Rasoul, M. (2007). Insecticidal, antifeedant and antifungal activities of two glucosides isolated from the seeds of Simmondsia chinensis. Industrial Crops and Products, 26(3), 345–350.

Abdel-Mageed, W. M., Bayoudi, S. A. H., Radwan, A. A., Salem-Behkit, M. M., Abd-Alrahman, S. H., Basuan, D. A., Sayad, H. M. (2014). Simmondisia chinensis: A rich source of bioactive flavonoid and lignan. Industrial Crops and Products. 60, 90-103.

Abdul-Hafeez, E., Karamova, N., & Ilinskaya, O. (2014). Antioxidant activity and total phenolic compound content of certain medicinal plants. International Journal of Biosciences, 5(1), 213–222.

Amić, D., Davidović-Amić, D., BeÅ›lo, D., Rastija, V., LuÄić, B., & Trinajstić, N. (2007) SAR and QSAR of the Antioxidant Activity of Flavonoids. Current Medicinal Chemistry, 14, 827-845

Al-Qizwini, H., Ekbal, A., Mhaidat, N., & Maraqa, A. (2014). Antioxidant and antimicrobial activities of Jordanian Simmondsia chinensis. European Scientific Journal, 10, 229-241.

Ariansyah, A., Lestari, Y., Batubara, I., Egra, S., (2019) Antioxidant and Antiglycation Activity of Rhizosphere and Endophytic Actinobacteria of Xylocarpus granatum. Biosaintifika. 11(2): 202-210.

AOAC. Official Methods of Analysis. 18th edn. Association of Analytical Chemists. Washington DC. USA: 2005

Banjarnahor, S. D., & Artanti, N. (2014). Antioxidant properties of flavonoids. Medical Journal of Indonesia, 23(4), 239-244.

Belhadj, S., Hentati, O., Hamdaoui, G., Fakhreddine, K., Maillard, E., Dal, S., & Sigrist, S. (2018). Beneficial effect of jojoba seed extracts on hyperglycemia-induced oxidative stress in RINm5f Beta cells. Nutrients, 10(3), 1-17.

Elliger, C. A., Waiss, J., & Lundin, R. E. (1974). Cyanomethylene cyclohexyl glucosides from Simmondsia californica Phytochemistry, 13, 2319-2320.

Kara, Y. (2017). Phenolic contents and antioxidant activity of Jojoba (Simmondsia chinensis). International Journal of Secondary Metabolite, 4(2), 142-147.

Mageed, W., Bayoumi, S., Al-Wahaibi, L., Li, L., Sayed, H., Abdelkader, M., El-Gamal, A., Liu, M., Zhang, J., Zhang, L., & Liu, X. (2016). Noncyanogenic cyanoglucoside cyclooxygenase inhibitors from Simmondsia chinensis. Organic Letters, 18(8), 1728-1731.

Mageed, W., Bayoumi, S., Radwan, A., Bekhit, S., Alrahman, S., & Sayed, S. (2014a). Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pacific Journal of Tropical Medicine, 7, 521-526.

Mageed, W., Bayoumi, S., Radwan, A., Bekhit, S., Alrahman, S., Basudan, O., & Sayed, S. (2014b). Simmondsia chinensis: a rich source of bioactive flavonoids and lignans. Industrial Crops and Products, 60(2014), 99-103.

Manoharan, S., Vishnupriya, V., & Gayathri, R. (2016). Phytochemical analysis and in vitro antioxidant activity of jojoba oil. Journal of Pharmaceutical Sciences and Research, 8(6), 512–516.

Maser, W. (2014). Aplikasi metabolomic untuk mengidentifikasi komponen bioaktif: komponen antibakteri dari ekstrak buah takokak (Solanum torvumSwart) [Tesis]. Bogor (ID): Institut Pertanian Bogor

Molyneux, P. (2004). The use of the stable free radical diphenylpicryl-hydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal of Science and Technology. 26(2), 211-21.

Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2) 443-449.

Sudarmadji. (2010). Analisa Bahan Makanan dan Pertanian. Yogyakarta (ID): Liberty Yogyakarta.

Tawalbeh, M., Allawzi, M. A., & Kandah, M. I. (2005). Production of activated carbon from jojoba seed residue by chemical activation residue using a static bed reactor. Journal of Applied Sciences, 5, 482-487.

Tillah, M., Batubara, I., & Sari, R.K. (2017) Antimicrobial and Antioxidant Activities of Resins and Essential Oil From Pine (Pinus merkusii, Pinus oocarpa, Pinus insularis) and Agathis (Agathis loranthifolia). Biosaintifika: Journal of Biology & Biology Education. 9, 134-139.

Werdhasari, A. (2014). Peranan antioksidan bagi kesehatan. Jurnal Biotek Medisiana Indonesia. 3(2), 59- 68.

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