Efek Akut Pemberian Asam Amino Citrulin Alami Terhadap Kekuatan Otot

Anies Setiowati, Sri Sumartiningsih

Abstract


Tujuan penelitian untuk menganalisa efek akut asam amino sitrulin alami terhadap kekuatan otot. Metode penelitian dengan desain -post test controlled group design.  Sampel penelitian adalah mahasiwa IKOR FIK  dibagi secara acak menjadi 2 kelompok  yaitu kelompok kontrol  dan kelompok sitrulin. Perlakuan pada kelompok sitrulin berupa pemberian jus semangka 428 ml (600-700 g daging buah semangka) kandungan sitrulin sebesar 1 mg. sedang pada kelompok control diberikan placebo yaitu air sirup. Jus semangka ataupun air sirup diberikan 60 menit sebelum dilakukan tes kekuatan otot yaitu kekuatan otot tungkai, punggung, bahu dan genggam tangan dengan menggunakan Dynamometer. Data  dianalisis diuji T-test dengan SPSS. Hasil penelitian: rerata kekuatan otot total diperoleh dari hasil penjumalahan kekuatan otot punggung, tungkai, bahu, genggam tangan. Retata kekuatan otot total kelompok kontrol 362,98±87,26 kg, kelompok perlakuan critrulline alami (semangka) 378,46±128,23, p=0,782. Tidak terdapat perbedaan efek akut asam amino sitrulin alami terhadap kekuatan otot


Keywords


Citrulin, semangka, kekuatan

Full Text:

PDF

References


Aru W Sudoyo dkk. 2006. Buku Ajar Ilmu Penyakit Dalam Jilid III Edisi IV. Pusat Penerbit Departemen Ilmu Penyakit Dalam FKUI: 1948-1953.

Almatsier S. 2003. Prinsip Dasar Ilmu Gizi. Jakarta. Gramedia Pustaka Utama.

Bailey SJ, Vanhatalo A, Winyard PG, Jones AM. The nitrate-nitrite-nitric oxide pathway: its role in human exercise physiology. Eur J Sport Sci. 2011;12(4):309–20

Bescós R, Sureda A, Tur JA, et al. The effect of nitric-oxide-related supplements on human performance. Sports Med. 2012;42:99–12. DOI: 10.2165/11596860-000000000-00000 [Crossref]

Cabral, L.J.A., Cisneros, R.A., Camacho,R., Gonzalez, S., Sanchez,S., Trejo, M. Modification of Fatigue Indicators using Citrulline Malate for High Performance Endurance Athletes 2012; p:1-4. Available at : www.sciencediret.com.

Chappell, AJ, Allwood DM, Johns R, Brown S, Sultana K, Anand A, Simper T Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females Journal of the International Society of Sports Nutrition volume 15, Article number: 42 (2018)

Collins, J. K., Wu, G., Perkins-Veazie, P., Spears, K., Claypool, P. L., Baker, R. A., & Clevidence, B. A. Watermelon consumption increases plasma arginine concentrations in adults. Nutrition, 2007; 23(3), 261–266.

Cutrufello, P. T., Gadomski, S. J. & Zavorsky, G. S. The Effect of L-Citrulline and Watermelon Juice Supplementation on Anaerobic and Aerobic Exercise Performance. J. Sports Sci. 33, 1459–1466 (2015).

Cunniffe B, Papageorgiou M, O’Brien B, Davies NA, Grimble GK, Cardinale M. Acute citrulline-malate supplementation and high-intensity cycling performance. J Strength Cond Res. 2016;30(9):2638–47.

Curis E, Nicolis I, Moinard C, Osowska S, Zerrouk N, Benazeth S, et al. Almost all about citrulline in mammals. Amino Acids 2005;29:177–205.

Davis, A.R., et al. L-Citrulline Levels in Watermelon Cultigens Tested in Two Environments. Hort Science 46(12):1572–1575. 2011.

Diaz Tarazona, M.P., Alacid, F., Carraco, M., Martinez I, Aguayo E. Watermelon Juice : A Potential Functional Drink for Sore Muscle Relief in Athletes. Journal of Agricultural and Food Chemistry. 2013; p:13-16.

El-Hattab, A. W., Hsu, J. W., Emrick, L. T., Wong, L.-J. C., Craigen, W. J., Jahoor, F., & Scaglia, F. Restoration of impaired nitric oxide production in MELAS syndrome with citrulline and arginine supplemsupplementation. Molecular Genetics and Metabolism, 2012: 105(4), 607–614.

Fila, W.A., Itam, E.H., Johnson, J.T., Odey, M.O., Effiong, E E, Dasofunjo, K, Ambo, E.E. Comparative Proximate Compositions of Watermelon Citrullus lanatus, Squash Cucurbita Pepo’l, and Rambutan Nephelium Lappaceum’, International Journal of Science and Technology, 2013, vol. 2, no.1, pp. 81 – 88.

Hasanah, U. Perbedaan Nilai Kelelahan Anaerobik Atlet Sepak Bola yang Diberikan dan tidak Diberikan Buah Semangka Merah (Citrullus lanatus). (Universitas Diponegoro, 2015).

Glenn, J. M. et al. Acute Citrulline Malate Supplementation Improves Upper and Lower Body Submaximal Weightlifting Exercise Performance in Resistance Trained Females. Eur. J. Nutr. 56, 775–784 (2017).

Giannesini, B., Izquierdo, M., Le Fur, Y., Cozzone, P. J., Verleye, M., Le Guern, M.-E, Bendahan, D. Beneficial effects of citrulline malate on skeletal muscle function in endotoxemicrat. European Journal of Pharmacology, 2009; 602(1), 143–147.

Giaanesini ,B., Cozzone ,J.P,, Verleye,M., Bendahan,D. , Yann Le fur, et al.Citrulline Malate Supplementation Increases Muscle Efficiency in Rat Skeletal Muscle. European Journal of Pharmacology 667, 2011; 100–104.

Gonzalez AM, Spitz RW, Ghigiarelli JJ, Sell KM, Mangine GT. Acute effect of citrulline malate supplementation on upper-body resistance exercise performance in recreationally resistancetrained men. J Strength Cond Res. 2017. https ://doi.org/10.1519/ jsc.00000 00000 00237 3 (ePub ahead of print)

Guyton, A.C.and Hall, J.E., 2006. Text book of medical physiology, eleventh edition. Elseier Saunders. Philladelpia.

Kaore, S. N., Amane, H. S. & Kaore, N. M. Citrulline: Pharmacological Perspectives and its role as an Emerging Biomarker in Future. Fundam. Clin. Pharmacol. 27, 35–50 (2012).

Jordan MG, Michelle G, Austen J, Matthew S. St & Jennifer L. . Acute citrulline-malate supplementation improves maximal strength and anaerobic power in female, masters athletes tennis players. Journal European Journal of Sport Science Volume 16, 2016 - Issue 8

Joyner MJ, Casey DP. Regulation of increased blood flow (hyper-emia) to muscles during exercise: a hierarchy of competing physi-ological needs. Physiol Rev. 2015;95(2):549–601.

Lubis Munar, Siska Mayasari Lubis. Asidosis Laktat. Majalah Kedokteran Nusantara volume 39. Medan. Departemen Ilmu Kesehatan Anak Fakultas Kedokteran USU. 2006; p: 1-2. Available from. URL : http://repository.usu.ac.id

Lutgens L., Lambin P. Biomarkers for radiation-induced small bowel epithelial damage: an emerging role for plasma Citrulline. World J Gastroenterol 2007;13:3033–42

Mandel, H.; Levy, N.; Izkovitch, S.; Korman, S. H.Elevated plasma citrulline and arginine due to consumption of Citrullus vulgaris (watermelon) J. Inherit. Metab. Dis. 2005, 28, 467– 72

Meneguello MO, Mendoca JR, Lancha AH, et al. Effectof arginine, ornithine and citrulline supplementationupon performance and metabolism of trained rats. CellBiochem Funct.2003;21:85–91.

Marks DB, et al. Alih Bahasa Brahm U Pendit. 2000. Biokimia kedokteran dasar. Sebuah pendekatan klinis, Jakarta: EGC:321-336,481-545.

Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W., 2003. Harper’s Illustrated biochemistry, twenty sixt edition. McGraw-Hill Companies.

Pérez-Guisado, J., & Jakeman, P. M. Citrulline Malate Enhances Athletic Anaerobic Performance and Relieves Musclesoreness. Journal of Strength and Conditioning Research, 2010:24(5), 1215–1222.

Rizal dan Segalita. Peran Asam Amino Sitrulin dalam Meningkatkan Performa Olahraga Pada Atlet Amerta Nutr (2018) 299-306 299 DOI : 10.2473/amnt.v2i4.2018.299-306

Rimando Agnez M, Veazie Perkins PM. Determination of Citrulline in Watermelon Rind. Journal of Chromathography. 2005: 196-200. Available at : www.sciencedirect.com.

Romero ,M.J,, Platt, D.H., Caldwell R.B., Caldwell R.W,. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275–90.

Roug_e C, Des Robert C, Robins A, Le Bacquer O, Volteau C, De la Cochetiere MF. Manipulation of citrulline availability in humans. Am J Physiol Gastrointest Liver Physiol 2007;293:G1061–7.

Safdar A, Little, J. P., Stokl A. J, Hettinga B. P., Akhtar M., Tarnopolsky M. A., Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. J. Biol. Chem. 2011, 286, 10605.

Sirait, P. A., Abrori, C. & Suswati, E. Pengaruh Pemberian Jus Semangka terhadap Kelelahan Otot dan Delayed Onset Muscle Soreness setelah Latihan Beban. E-Jurnal Pustaka Kesehat. 1, 132–135 (2015).

Suzuki, T., Morita, M., Kobayashi, Y. & Kamimura, A. Oral L-citrulline Supplementation Enhances Cycling Time Trial Performance in Healthy Trained Men: Double-Blind Randomized Placebo-Controlled 2-Way Crossover Study. J. Int. Soc. Sports Nutr. 13, 1–8 (2016).

Takeda K, Machida M, Kohara A, et al. Effects of citrul-line supplementation on fatigue and exercise perfor-mance in mice. J Nutr Sci Vitaminol.2011;57:246–250

Urdampilleta A, Armentia I, Gómez-Zorita S, et al. Lafatiga muscular en los deportistas: métodos físicos,nutricionales y farmacológicos para combatirla. ArchMed Deport.2015;32:36–43

Villareal MO, Matsukawa T, Isoda H lâ€Citrulline Supplementationâ€Increased Skeletal Muscle PGCâ€1α Expression Is Associated with Exercise Performance and Increased Skeletal Muscle Weight. Mol Nutr Food Res. 2018 Jul; 62(14): 1701043.

Wax, B., Kavazis, A. N. & Luckett, W. Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained Males. J. Diet. Suppl.13,269–282 (2015)




DOI: https://doi.org/10.15294/miki.v10i2.27120

Refbacks

  • There are currently no refbacks.




Published by:
Department of Sport Science, Universitas Negeri Semarang
Gd. F1 Lt. 1 FIK-UNNES, Jalan Raya Sekaran Gunungpati Semarang Indonesia 50229, Telp/Fax: (024) 8508007

 

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.