Effect of Ultrasonication Extraction Time on Determination of Flavonoid Levels in Ciplukan Plants

Ummul Habibah Hasyim, Fatma Sari, Ika Kurniaty, Annisya Ramadhani

Abstract

Ciplukan contains bioactive substances in the form of flavonoids, saponins, alkaloids, polyphenols, vitamin C, stearic acid, palmitic acid. Bioactive substances from natural ingredients are known to function as immunomodulators that can increase the body's immune system, activate the body's natural defenses and restore immune system imbalances. Immunomodulators are important in studies related to the issue of the coronavirus disease 19 (Covid-19) pandemic. The purpose of this study was to determine the effect of the extraction time on the ultrasonic method on the flavonoid yield of ciplukan plants using methanol as a solvent. The method used is ultrasonication extraction with a variable extraction time. The analysis was carried out by qualitative analysis using a solution of qursetin to determine the concentration of flavonoids. The results of the study obtained the optimum flavonoid concentration at the extraction time of 15 minutes

Keywords

Ciplukan;extraction;flavonoid;physalis angulate;ultrasonic

Full Text:

PDF

References

Aminah, A., Tomayahu, N., Abidin, Z. 2011. Penetapan Kadar Flavonoid Total Ekstrak Etanol Kulit. Jurnal Fitofarmaka Indonesia. 4(2): 226-230.

Ashley, K., Andrews, R., Cavazos, L., Demange, M. 2001. Ultrasonic extraction as a sample preparation technique for elemental analysis by atomic spectrometry. Journal of Analytical At Spectrom. 16(10): 1147-1153.

Kusumaningtyasa, R. W., Laily, N., Limandha, P. 2015. Potential of Ciplukan (Physalis angulata L.) as Source of Functional Ingredient. Procedia Chemistry. 14: 367-372.

Ridwanuloh, F. 2019. Isolasi Dan Identifikasi Senyawa Flavonoid Dari Batang Ciplukan (Physalis Angulata L.). Jurnal Sains dan Ilmu Farmasi. 4(1): 288-296.

Sharma, V., Janmeda, P. 2014. Extraction, isolation and identification of flavonoid from Euphorbia neriifolia leaves. Arabian Journal of Chemistry. 10(4): 509-5014.

Verdiana, M., Widarta, I. W., Permana, I. D. 2018. Pengaruh Jenis Pelarut Pada Ekstraksi Menggunakan Gelombang Ultrasonik Terhadap Aktivitas Antioksidan Ekstrak Kulit Buah Lemon (Citrus Limon) (Linn.) Burm F.). Jurnal Ilmu dan Teknologi Pangan. 7(4): 213-222.

Zheng, L. L., Wen, G., Yuan, M. Y., Gao, F. 2016. Ultrasound-assisted extraction of total flavonoids from corn silk and their antioxidant activity. Journal of Chemistry. 2015: 1-5.

DOI: https://doi.org/10.15294/jbat.v11i1.35254

Refbacks

  • There are currently no refbacks.


Bookmark and Share