Socio-demographic Factors Associated with Loss to Follow up Anti Retro Viral Therapy among People Living with HIV and AIDS in Semarang City
(1) Universitas Negeri Semarang
(2) Universitas Negeri Semarang
(3)[email protected]
Abstract
Longlife Anti Retro Viral (ARV) treatment is an important component of Human Immunodeficiency Virus (HIV) care. Loss to follow up (LTFU) defined as not taking ARV refill for 3 months or longer from the last attendance for refill and not yet classified as dead or transferred out, this causes morbidity and mortality related to Acquired Immune Deficiency Syndrome (AIDS). The incidence of LTFU in ARV therapy among people living with HIV and AIDS (PLWHA) in Semarang City 924 people (21%) (WHO target LTFU <20%). The aim of this research is to analyze education level, employment status and distance from residence to health services that affecting loss to follow-up of ARV therapy among people living with HIV and AIDS in Semarang City. The research used case control design. The sample of the research was 134 (67 cases and 67 controls) respondents obtained by purposive sampling technique. Technique for collecting the data were interview and questionnaire. Chi square and logistics regression test were used in analyzing the data. The result of the research showed that there were significant influences in the variables of education (p = 000), employment status (p = 0,000), distance from home to health services (p = 0.009 affect loss to follow up of antiretro viral therapy among people living with HIV and AIDS in Semarang City. Multivariate models showed the most influential factors was education level (p= 0,000. OR = 6.270). A treatment literacy program should be emphasized to people living with HIV and AIDS who are starting treatment and during treatment ARV.                     Â
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Alvarez, U., Gerardo., Praveen, K. N., Raghavakalyan, P., & Manoranjan, M. (2013). Factors Associated with Attrition, Mortality, and Loss to Follow up after Antiretroviral Therapy Initiation: Data from an HIV Cohort Study in India. Global Health Action, 6 (21682), 1–8.
Bam, K., Rajesh M., Rajbhandari., Dibesh B., Karmacharya & Sameer, M. D. (2015). Strengthening Adherence to Anti Retroviral Therapy (ART) Monitoring and Support: Operation Research to Identify Barriers and Facilitators in Nepal Health Systems and Services in Low and Middle Income Settings. BMC Health Services Research , 15(1), 1–11.
Bekolo, C. E., Webster, J., Batenganya, M., Gerald, E. S., & Basile, K. ( 2013). Trends in Mortality and Loss to Follow-up in HIV Care at the Nkongsamba Regional Hospital, Cameroon. BMC Research Notes, 6(1).
Berheto, T. M., Haile, D. B., & Mohammed, S. (2014). Predictors of Loss to Follow-up in Patients Living with HIV/AIDS after Initiation of Antiretroviral Therapy. North American Journal of Medical Sciences, 6(9), 453–59.
Bucciardini, R., Fragola, V., Abegaz, T., Lucattini, S., Halifom, A., Tadesse, E., Berhe, M., Pugliese, K., Fucili, L., Gregorio, M. D., etc. (2017). Predictors of Attrition from Care at 2 Years in a Prospective Cohort of HIVinfected Adults in Tigray, Ethiopia. BMJ Global Health, 2, 1–9.
Bygrave, H., Kranzer K., Hilderbrand K., Whittall J., Jouquet G., Goemaere E., Vlahakis N., Triviño L., Makakole., L & Ford N. (2010). Trends in loss to follow-up among migrant workers on antiretroviral therapy in a community cohort in Lesotho. PLoS ONE, 5(10), 3-7.
Conley, N., Jeanne, B. P., Pavlinac., Guthrie B. L., Rome, D., Anthony, M., Muiru N., Robert Y., Bosire C. R., Gatuguta, A., & Farquhar, C. (2012). Distance from Home to Study Clinic and Risk of Follow-up Interruption in a Cohort of HIV-1-Discordant Couples in Nairobi, Kenya. PLoS ONE,7(8), 4–11.
Dinas Kesehatan Kota Semarang. Laporan Tahunan Pencegahan dan Penanggulangan Penyakit Tahun 2019. Semarang : Dinas Kesehatan Kota Semarang, 2019.
Ford, N., Darder, M., Spelman., Maclean, E., Mills, E., & Boulle, A. (2010). Early Adherence to Antiretroviral Medication as a Predictor of Long-Term HIV Virological Suppression : Five-Year Follow Up of an Observational Cohort. PLoS ONE, 5(5), 1–4.
Gesesew, H. A., Paul, W., Kifle, W., & Lillian, M. (2017). Prevalence, Trend and Risk Factors for Antiretroviral Therapy Discontinuation among HIV-Infected Adults in Ethiopia in 2003-2015. PLoS ONE, 12(6), 1–16.
Girum, T., Yasin, F., Wasie, A., Shumbej, T., Bekele, F., & Zeleke, B. (2020). The Effect of Universal Test and Treat Program on HIV Treatment Outcomes and Patient Survival among a Cohort of Adults Taking Antiretroviral Treatment ( ART ) in Low Income Settings of Gurage Zone, South Ethiopia. AIDS Research and Therapy, 17:19, 1–9.
Handayani, L., Ahmad, R. A., & Subronto, Yanri, W. (2017). Faktor Risiko Loss to Follow up Terapi ARV Pada Pasien HIV Risk Factors for Loss to Follow up of Antiretroviral Therapy in HIV Patients. Journal of Community Medicine and Public Health), 33 (4),173-180.
Hassan, A. S., Fielding, K. L., Thuo, N. M., Nabwera, H. M., Sanders, E. J., & James, A. B. (2012). Early Loss to Follow-up of Recently Diagnosed HIV-Infected Adults from Routine Pre-ART Care in a Rural District Hospital in Kenya: A Cohort Study. Tropical Medicine and International Health, 17(1), 82–93.
Hønge, B. L., Jespersen S., Nordentoft P. B., Medina, C., da Silva, D., & da Silva, Z. J. (2013). Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV- infected patients in Guinea-Bissau: a 7-year retrospec- tive cohort study. BMJ Open, 3(10), 1–10.
Kementrian Kesehatan RI. (2019). Kepmenkes Nomor HK.01.07/Menkes/90/2019 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana HIV. Kementerian Kesehatan Republik Indonesia, 1-220.
Kiwanuka, J., Waila, J. M., Kahungu, M. M., Kitonsa, J., & Kiwanuka, N. (2020). Determinants of Loss to Follow-up among HIV Positive Patients Receiving Antiretroviral Therapy in a Test and Treat Setting: A Retrospective Cohort Study in Masaka, Uganda. PLoS ONE, 15(4), 1–17.
Krishnan, S., Wu K M.S., Smurzynski, M., Bosch, R. J., Benson, C. A., Collier, A. C., Klebert, M. K., Feinberg, J., & Koletar, S. L. (2011). Incidence Rate of and Factors Associated with Loss to Follow-up in a Longitudinal Cohort of Antiretroviral-Treated HIV-Infected Persons: An AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) Analysis. HIV Clinical Trials, 12(4), 190–200.
Marson, K. G., Tapia, K., Kohler, P., McGrath Christine, J., John-Stewart., Barbra, G. C., Richardson., Njoroge, J. W., James., Kiarie., Sakr Samah R., & Chung, M. H. (2013). Male, Mobile, and Moneyed Loss to Follow-Up vs. Transfer of Care in an Urban African Antiretroviral Treatment Clinic. PLoS ONE, 8(10), 2–9.
Megerso, A., Garoma, S., Eticha, T., Workineh, T., Daba, S., Tarekegn, M., & Habtamu, Z. (2016). Predictors of Loss to Follow-up in Antiretroviral Treatment for Adult Patients in the Oromia Region , HIV/AIDS. Research and Palliative Care, 8, 83–92.
Mekonnen, N., Mohamed, A., Eleyias, S., & Adhanom, G. B. (2019). Incidence and Predictors of Loss to Follow ‑ up among HIV Infected Adults after Initiation of First Line Anti ‑ Retroviral Therapy at University of Gondar Comprehensive Specialized Hospital Northwest Ethiopia, 2018 : Retrospective Follow up Study. BMC Research Notes, 12 (111), 1–7.
Montaner, J. S.G., Lima, V. D., Harrigan, P. R., Lourenc, L., Yip, B., Nosyk, B., Wood, E., Kerr Thomas., Shannon, K., Moore, D., Hogg, R. S., Barrios, R., Gilbert, M., Krajden, M., Gustafson, R., Daly, P., & Kendall, P. (2014). Expansion of HAART Coverage Is Associated with Sustained Decreases in HIV/AIDS Morbidity, Mortality and Hiv Transmission: The ‘HIV Treatment as Prevention’ Experience in a Canadian Setting. PLoS ONE, 9(2), 1–10.
Ochieng-ooko, V., Ochieng, D., Siddle, J. E., Holdworth, M., Wools, L. K., Silka, A. M., Yiannoutsos, C. T., Owiti, M., Kimaiyo, S., & Braitstein, P. (2010). Influence of Gender on Loss to Follow-up in a Large HIV Treatment Programme in Western Kenya. Bulletin World Health Organization, 88, 681–688.
Panditrao, M., Darak, S., Kulkarni, V., Kulkarni, S., & Parchure, R. (2011). Socio-Demographic Factors Associated with Loss to Follow-up of HIV-Infected Women Attending a Private Sector PMTCT Program in Maharashtra, India. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV , 23(5), 593–600.
Rosiana, A., & Muclis, S. (2014). Faktor – Faktor Yang Mempengaruhi Lost To Follow-Up Pada Pasien HIV/AIDS Dengan Terapi ARV Di RSUP Dr Kariadi Semarang.†Jurnal Kedokteran Diponegoro, 3(1).
Shaweno, T., & Debebe, S. (2015). When Are Patients Lost to Follow-up in Pre Antiretroviral Therapy Care? A Retrospective Assessment of Patients in an Ethiopian Rural Hospital. Infectious Diseases of Poverty, 4(1), 1–8.
Tran, D. A., Ngo Anh Duc., Shakeshaft, A., Wilson, D. P., Doran, C., & Zhang, L. (2013). Trends in and Determinants of Loss to Follow Up and Early Mortality in a Rapid Expansion of the Antiretroviral Treatment Program in Vietnam : Findings from 13 Outpatient Clinics. PLoS ONE, 8(9).
Ware, N. C., Wyatt, M. A., Geng, E. H., Kaaya, S. F., Agbaji, O. O., Muyindike, R. W., Chalamilla, G., & Agaba, P. A. (2013). Toward an Understanding of Disengagement from HIV Treatment and Care in Sub-Saharan Africa: A Qualitative Study. PLoS Medicine, 6 (21682), 10(1).
WHO. (2016). Consolidated Guidelines on The Use of Antiretroviral Drugs for Treating and Preventing HIV Infection 2016 Recommendations for A Public Health Approach Second Edition. https://www.who.int/hiv/pub/vct/en/
WHO. (2019). Progress report on HIV, viral hepatitis and sexually transmitted infections, 2019. Accountability for the global health sector strategies, 2016–2021. https://www.who.int/hiv/strategy2016-2021/progress-report-2019/en/
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