Ecological Study on Factors Related to the Mortality of Rabies in North Sulawesi Province at the Year of 2015 to 2017

Noer Syafiiah Tiarma(1), Putri Bungsu Machmud(2),

(1) University of Indonesia Public Health Faculty Epidemiology Department
(2) University of Indonesia


Indonesia, which is part of the region, contributes 25 provinces including areas that have not been free from the endemic of rabies. One of the provinces that ranked top in the cases of rabies was North Sulawesi. Therefore, this study aims to find correlations between factors related to the prevalence of rabies deaths in North Sulawesi Province in 2015 - 2017. This study used a mixed ecological study design by applying the principle of total sampling to 15 districts/citiesin North Sulawesi. The results of the study found that there was a negative and weak strength correlation on the anti rabiesvaccine coverage factor (r = 0.279), moderate strength correlation on the ratio of health care workers (r = 0.345), and the ratio of health care facilities (r = 0.320) to the mortality of rabies. While the sex ratio factor is positive and has moderate strength (r = 0.365) against the mortality of rabies. The new findings of health care facility and health care workers that have a moderate strength correlation need to be included in the prevention of rabies approach because it can help to facilitate washing wounds treatment. 


Rabies, Ecology, correlation, Mortality, Sulawesi

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Barbosa Costa, G., Gilbert, A., Monroe, B., Blanton, J., Ngam Ngam, S., Recuenco, S., et al. (2018). The influence of poverty and rabies knowledge on healthcare seeking behaviours and dog ownership, Cameroon. PloS one.

Fu, Z. (1997). Rabies and Rabies Research: Past, Present, Future. Vaccine(15), 20-24.

Kementerian Kesehatan RI. (2016). InfoDATIN Kementerian Kesehatan RI. Jakarta: Kementerian Kesehatan RI.

Kementerian Kesehatan RI. (2017). Buku Saku Petunjuk Teknis Penatalaksanaan Kasus Gigitan Hewan Penular Rabies di Indonesia. Jakarta: Kemenkes RI.

Kementerian Kesehatan RI. (2018, October 3). Rabies Penyakit Paling Mematikan di Dunia. Retrieved November 16, 2018, from

Knobel, D. L., Arega, S., Reininghaus, B., Simposin, G. J., Gessner, B. D., Stryhn, H., et al. (2017). Rabies vaccine is associated with decreased all-cause mortality in dogs,. Elsevier, 3844-3849.

Montgomery, J., Zhang, Y., Well, E., Liu, Y., Clayton , J., & Wang, X. (2012). Human rabies in Tianjin, China. Journal of Public Health, 505-511.

Pan American Health Organization. (2017, June 27). Brazil donates vaccines against human rabies to Haiti, with the support of Panaftosa/PAHO. Retrieved December 22, 2018, from〈=pt

Riley, S., John, H., & David, M. (1998). Population density, survival, and rabies in raccoons in an urban national park. Canadian Journal of Zoology-revue Canadienne De Zoologie, X, 1153-64.

SEARO World Health Organization. (2012). Strategic Framework for Elemination of Human Rabies Transmitted by Dogs in South East Asian Region. New Delhi: SEARO WHO.

Wang, X., Ding, S., Li, Z., Wang, L., Kou, Z., & Feng, K. (2010). Human rabies epidemiology in Shandong Province. China Japan Journal of Infectious Disease, 323-326.

World Health Organization. (2013). Rabies: General Introduction. Retrieved 12 2018, from

Yin, C., Zhou, H., Wu, H., Tao, X., Rayner, S., & Wang, S. (2012). Analysis on factors related to rabies epidemic in China from 2007-201. Virologica Sinica, 132-143.

Zaidi, S., Labrique, A., Khowaja, S., Lotia-Farrukh, I., Irani, J., & Salahuddin, N. (2013). Geographic variation in access to dog-bite care in Pakistan and risk of dog-bite exposure in Karachi:prospective surveillance using a low-cost mobile phone system. PLoS Neglected Tropical Disease, 2574.


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