Email this article 
Urban Air Pollution and Testosterone Plasma Level of Traffic Policemen in Jakarta
(1) Faculty of Public Health, University of Indonesia
(2) University of Indonesia
(3) University of Indonesia
(4) Nagoya University
Abstract
This study aims to investigate the concentration of traffic air pollution and the level of testosterone, fasting glucose, cortisol, and lipid profile among traffic police in Jakarta. Testosterone plasma and blood biochemicals in traffic police and the police officer were analyzed using ELISA kit. Air quality data from the Regional Environmental Agency (BPLHD) Jakarta 2012 were used for the characterization of exposure. The analysis used a t-test and linear regression test to show the relationship levels of pollutants exposure with the effects of reproductive dysfunction (p<0.05). The average plasma levels of testosterone in the traffic police 543.6 ± 170.5 mg/dL, which is higher than the police at the office 456.2 ± 133.2 mg/dL. The average plasma cholesterol levels of police at the office is 212.3 ± 42.0 mg/dL, which is higher than the traffic police 200.0 ± 40.2 mg/dL. On average fasting glucose levels police at the office is 90.0 ± 13.1 mg/dL, while traffic police 84.2 ± 5.9 mg/dL. The testosterone levels of traffic police are higher than the official police, and traffic police exposed to pollutants have lower fasting glucose levels than police officers in offices. Keywords: PM, plasma testosterone, reproductive function.
Keywords
Full Text:
PDFReferences
Anderson, J. O., Thundiyil, J. G., & Stolbach, A. (2012). Clearing the Air: A Review of the Effects of Particulate Matter Air Pollution on Human Health. Journal of Medical Toxicology, 8(2), 166-175.
Ärnlöv, J., Sundström, J., Ingelsson, E., & Lind, L. (2011). Impact of BMI and the Metabolic Syndrome on the Risk of Diabetes in Middle-Aged Men. Epidemiology/Health Services Research, 34(1), 61-65.
Badan Pusat Statistik Provinsi DKI Jakarta. (2015). Statistik Transportasi DKI Jakarta 2015. Jakarta: Badan Pusat Statistik Provinsi DKI Jakarta.
Bell, J., Kivimaki, M., & Hamer, M. (2014). Metabolically Healthy Obesity and Risk of Incident Type 2 Diabetes: A Meta-analysis of Prospective Cohort Studies. Obesity Reviews, 15(6), 504-515.
Cassee, F. R., He´roux, M.-E., M. E.-N., & Kelly, F. J. (2013). Particulate Matter Beyond Mass: Recent Health Evidence on the Role of Fractions, Chemical Constituents and Sources of Emission. Inhalation Toxicology, 25(14), 802-812.
Donaldson, K., Tran, L., Jimenez, L. A., Duffin, R., Newby, D. E., Mills, N., . . . Stone, V. (2005). Combustion-Derived Nanoparticles: A Review of Their Toxicology Following Inhalation Exposure. Particle and Fiver Toxicology, 2(10), 1-14.
Gao, F., Li, G., Liu, C., Gao, H., Wang, H., Liu, W., . . . Li, W. (2018). Autophagy Regulates Testosterone Synthesis by Facilitating Cholesterol Uptake in Leydig Cells. Journal of Cell Biology, 217(6), 2103-2119.
Ito, Y., Ramdhan, D. H., Yanagiba, Y., Yamagishi, N., Kamijima, M., & Nakajima, T. (2011). Exposure to Nanoparticle-Rich Diesel Exhaust may Cause Liver Damage. Japanese Journal of Hygiene, 66(4), 638-642.
Jung, U. J., & Choi, M.-S. (2014). Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease. International Journal of Molecular Sciences, 15(4), 6184-6223.
Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016). Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus. Endocrine Reviews, 37(3), 278-316.
Kim, K.-H., Kabir, E., & Kabir, S. (2015). A Review on the Human Health Impact of Airborne Particulate Matter. Environment International, 74, 136-143.
Makki, K., Froguel, P., & Wolowczuk, I. (2013). Adipose Tissue in Obesity-Related Inflammation and Insulin Resistance: Cells, Cytokines, and Chemokines. International Scholarly Research Notices, 2013, 1-12.
Merhi, Z., Bazzi, A., Moseley-LaRue, R., Moseley, A. R., Smith, A. H., Zhang, J., & Ruggiero, M. (2018). Ozone Therapy: Overview of its Potential Utility in Male Reproduction. American Journal of Immunology, 14, 15-25.
Ramdhan, D. H. (2014). Penelitian Genom dan Implikasinya dalam Kesehatan Masyarakat di Indonesia. Kesmas: National Public Health Journal, 9(1), 1-5.
Ramdhana, D. H., Ito, Y., Yanagib, Y., Yamagishi, N., Hayashi, Y., Li, C. M., . . . Nakajima, T. (2009). Nanoparticle-Rich Diesel Exhaust May Disrupt Testosterone Biosynthesis and Metabolism Via Growth Hormone. Toxicology Letters, 191(2-3), 103-108.
Rengaraj, D., Kwon, W.-S., & Pang, M.-G. (2014). Effects of Motor Vehicle Exhaust on Male Reproductive Function and Associated Proteins. Journal of Proteome Research, 14(1), 22-37.
Rosa, M. D., Zarrilli, S., Paesano, L., Carbone, U., Boggia, B., Petretta, M., . . . Lombardi, G. (2003). Traffic Pollutants Affect Fertility in Men. Human Reproduction, 18(5), 1055-1061.
Sancini, A., Tomei, F., Tomei, G., Ciarrocca, M., Palermo, P., Gioffrè, P. A., . . . Caciari, T. (2011). Exposure to Urban Stressors and Free Testosterone Plasma Values. International Archives of Occupational and Environmental Health, 84(6), 609-619.
Shah, A. S., Langrish, J. P., Nair, H., McAllister, D. A., Hunter, A. L., Donaldson, K., . . . Millsa, N. L. (2013). Global Association of Air Pollution and Heart Failure: A Systematic Review and Meta-Analysis. The Lancet, 382(9897), 1039-1048.
Song, J., Zha, X., Li, H., Guo, R., Zhu, Y., & Wen, Y. (2016). Analysis of Blood Glucose Distribution Characteristics and Its Risk Factors among a Health Examination Population in Wuhu (China). International Journal of Environmental Reserach and Public Health, 13(392), 1-9.
Tsukue, N., Toda, N., Tsubone, H., Sagai, M., Jin, W. Z., Watanabe, G., . . . Suzuki, A. K. (2001). Diesel Exhaust (DE) Affects the Regulation of Testicular Function in Male Fischer 344 Rats. Journal of Toxicology and Environmental Health, Part A, 63(2), 115-126.
Watanabe, N., & Oonuki, Y. (1999). Inhalation of Diesel Engine Exhaust Affects Spermatogenesis in Growing Male Rats. Environmental Health Perspectives, 107(7), 539-544.
Widziewicz, K., Rogula-Kozłowska, W., Loska, K., Kociszewska, K., & Majewski, G. (2018). Health Risk Impacts of Exposure to Airborne Metals and Benzo(a)Pyrene during Episodes of High PM10 Concentrations in Poland. Biomedical and Environmental Sciences, 31(1), 23-36.
Xu, X., Liu, C., Xu, Z., Tzan, K., Zhong, M., Wang, A., . . . Sun, a. Q. (2011). Long-term Exposure to Ambient Fine Particulate Pollution Induces Insulin Resistance and Mitochondrial Alteration in Adipose Tissue. Toxicological Sciences, 124(1), 88-98.
Yin, Y., Han, W., Wang, Y., Zhang, Y., Wu, S., Zhang, H., . . . Li, B. (2015). Identification of Risk Factors Affecting Impaired Fasting Glucose and Diabetes in Adult Patients from Northeast China. International Journal of Environmental Research and Public Health, 12(10), 12662-12678.
Zhou, J., Ito, K., Lall, R., Lippmann, M., & Thurston, G. (2011). Time-Series Analysis of Mortality Effects of Fine Particulate Matter Components in Detroit and Seattle. Environmental Health Perspectives, 119(4), 461-466.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 4.0 International License.