Email this article Effects of Exposure to the Hormone Cortisol in Pregnant Women on Body Weight and Length at Birth of Babies: A Prospective Study
(1) Universitas Megarezky
(2) Universitas Megarezky
(3) STIKES Nani Hasanuddin
(4) Universitas Megarezky
(5) IIK Pelamonia
(6) Universitas Megarezky
(7) Poltekkes Kemenkes Kendari
(8) Universitas Megarezky
Abstract
Other mental disorders with a reasonably high prevalence are pregnancy stress of 92.8% and anxiety of 32.6%. Pregnancy pressure can potentially cause low birth weight and small head circumference. In addition, stress during pregnancy will affect neurobehavioral development, ACTH, cortisol, norepinephrine, and epinephrine levels in neonates. This study aims to assess cortisol exposure in pregnancy with birth weight and birth length in infants. This study uses a cohort study approach. The sample in this study was the third-trimester pregnant women many as 152 respondents. The research instrument used checklist sheets and laboratory tests using the ELISA method. The resulting data were processed using the unpaired t-test and the Pearson correlation test. The results showed a correlation between cortisol levels and birth weight with a value of p = 0.004 <0.05 and a value of r = -0.230, indicating that both variables had a low correlation and a negative relationship. This means the higher the cortisol level, the lower the baby's birth weight. There is a correlation between cortisol levels and the baby's birth length with a value of p = 0.003 <0.05 and r = -0.239, showing that both variables have a low correlation and a negative relationship. The higher the cortisol level, the shorter the baby's birth length. Maintaining the mental health of pregnant women, primarily through family support and health workers, is essential to avoid excessive stress and depression during pregnancy.
Keywords
Full Text:
PDFReferences
Agung Suwardewa, T. G., Negara, K. S., Putra, I. G. M., Artana Putra, I. W., Pangkahila, E. S., & Maesa Putra, I. G. B. G. (2022). High Maternal Cortisol Serum Levels as A Risk Factor for Preterm Labor. European Journal of Medical and Health Sciences, 4(3), 75–77. https://doi.org/10.24018/ejmed.2022.4.3.1346
Arafa, A. E., ElMeneza, S. A., & Hafeez, S. A. EL. (2020). The Relation between Role of Serum Cortisol Level and Response to Various Respiratory Support Strategies among Preterm Infants. Open Journal of Pediatrics, 10(03), 504–514. https://doi.org/10.4236/ojped.2020.103051
Brummelte, S., Grunau, R. E., Zaidman-Zait, A., Weinberg, J., Nordstokke, D., & Cepeda, I. L. (2011). Cortisol levels in relation to maternal interaction and child internalizing behaviour in preterm and full-term children at 18 months corrected age. Developmental Psychobiology, 53(2), 184–195. https://doi.org/10.1002/dev.20511
Camerota, M., & Bollen, K. A. (2016). Birth weight, birth length, and gestational age as indicators of favourable fetal growth conditions in us sample. PLoS ONE, 11(4), 1–15. https://doi.org/10.1371/journal.pone.0153800
Caparros-Gonzalez, R. A., Lynn, F., Alderdice, F., & Peralta-Ramirez, M. I. (2022). Cortisol levels versus self-report stress measures during pregnancy as predictors of adverse infant outcomes: a systematic review. Stress, 25(1), 189–212. https://doi.org/10.1080/10253890.2022.2059348
Crane, J., Armson, A., Brunner, M., De La Ronde, S., Farine, D., Keenan-Lindsay, L., Leduc, L., Schneider, C., & Van Aerde, J. (2003). Antenatal corticosteroid therapy for fetal maturation. Journal of Obstetrics and Gynaecology Canada : JOGC = Journal d’obstétrique et Gynécologie Du Canada : JOGC, 25(1), 45–48. https://doi.org/10.1016/s1701-2163(16)31081-7
Hall, H., Munk, N., Carr, B., Fogarty, S., Cant, R., Holton, S., Weller, C., & Lauche, R. (2020). Maternal mental health and partner-delivered massage: A pilot study. Women and Birth. https://doi.org/https://doi.org/10.1016/j.wombi.2020.05.003
Heckmann, M., Wudy, S. A., Haack, D., Pohlandt, F., Heckmann, M., Wudy, S. A., Pohlandt, F., & Haack, D. (1999). Reference range for serum cortisol in well preterm infants. Archives of Disease in Childhood: Fetal and Neonatal Edition, 81(3), 171–174. https://doi.org/10.1136/fn.81.3.F171
Hwang, J. H., Lee, B. S., Kim, C. Y., Jung, E., Kim, E. A. R., & Kim, K. S. (2019). Basal serum cortisol concentration in very low birth weight infants. Pediatrics and Neonatology, 60(6), 648–653. https://doi.org/10.1016/j.pedneo.2019.03.003
Magee, L. A., Synnes, A. R., von Dadelszen, P., Hutfield, A. M., Chanoine, J. P., Côté, A. M., Devlin, A. M., Dorling, J., Gafni, A., Ganzevoort, W., Helewa, M. E., Hutton, E. K., Koren, G., Lee, S. K., Mcarthur, D., Rey, E., Robinson, W. P., Roseboom, T. J., Singer, J., … Moutquin, J. M. (2018). CHIPS-Child: Testing the developmental programming hypothesis in the offspring of the CHIPS trial. Pregnancy Hypertension, 14(April), 15–22. https://doi.org/10.1016/j.preghy.2018.04.021
Nath, A., Murthy, G. V. S., Babu, G. R., & Di Renzo, G. C. (2017). Effect of prenatal exposure to maternal cortisol and psychological distress on infant development in Bengaluru, southern India: a prospective cohort study. BMC Psychiatry, 17. https://doi.org/http://dx.doi.org/10.1186/s12888-017-1424-x
Ng, P. C., Wong, G. W. K., Lam, C. W. K., Lee, C. H., Wong, M. Y., Fok, T. F., Wong, W., & Chan, D. C. F. (1997). Pituitary-adrenal response in preterm, very low birth weight infants after treatment with antenatal corticosteroids. Journal of Clinical Endocrinology and Metabolism, 82(11), 3548–3552. https://doi.org/10.1210/jcem.82.11.4392
Pan, X. F., Tang, L., Lee, A. H., Binns, C., Yang, C. X., Xu, Z. P., Zhang, J. L., Yang, Y., Wang, H., & Sun, X. (2019). Association between fetal macrosomia and risk of obesity in children under 3 years in Western China: a cohort study. World Journal of Pediatrics, 15(2), 153–160. https://doi.org/10.1007/s12519-018-0218-7
Peterson, A. K., Toledo-Corral, C. M., Chavez, T. A., Naya, C. H., Johnson, M., Eckel, S. P., Lerner, D., Grubbs, B. H., Farzan, S. F., Dunton, G. F., Bastain, T. M., & Breton, C. V. (2020). Prenatal maternal cortisol levels and infant birth weight in a predominately low-income Hispanic cohort. International Journal of Environmental Research and Public Health, 17(18), 1–13. https://doi.org/10.3390/ijerph17186896
Phillips, D. I. W., Walker, B. R., Reynolds, R. M., Flanagan, D. E. H., Wood, P. J., Osmond, C., Barker, D. J. P., & Whorwood, C. B. (2000). Low birth weight predicts elevated plasma cortisol concentrations in adults from 3 populations. Hypertension, 35(6), 1301–1306. https://doi.org/10.1161/01.HYP.35.6.1301
Pitri Yola Zilfi, Ali Hirowati, dan D. (2019). Pengaruh Stres Terhadap Pertumbuhan Janin dan Kadar Kortisol Plasma Serum Tikus (Rattus norvegicus) Bunting. Jurnal Kesehatan Andalas, 8(3), 537–542.
Prabhu, S., George, L. S., Shyamala, G., Jose, T. T., & George, A. (2020). The effect of a prenatal psychosocial education program on postnatal depression, stress, and parenting self-efficacy in women in South India - A study protocol for a randomized controlled trial. Mental Health & Prevention, 20, 200194. https://doi.org/https://doi.org/10.1016/j.mhp.2020.200194
Shim, G. H. (2023). Does cord blood cortisol have a mediating effect on maternal prepregnancy body mass index and birth weight? Clinical and Experimental Pediatrics, 66(1), 24–25. https://doi.org/10.3345/cep.2022.00955
Shriyan, P., Sudhir, P., van Schayck, O. C. P., & Babu, G. R. (2023). Association of high cortisol levels in pregnancy and altered fetal growth. Results from the MAASTHI, a prospective cohort study, Bengaluru. The Lancet Regional Health - Southeast Asia, 100196. https://doi.org/10.1016/j.lansea.2023.100196
Woolhouse, H., Mercuri, K., Judd, F., & Brown, S. J. (2014). Antenatal mindfulness intervention to reduce depression, anxiety and stress: a pilot randomized controlled trial of the MindBabyBody program in an Australian tertiary maternity hospital. BMC Pregnancy and Childbirth, 14, 369. https://doi.org/10.1186/s12884-014-0369-z
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 4.0 International License.