Modeling Social, Health, and Vaccines Intervention in Time of Covid-19 Pandemic Impacted in Jakarta - Indonesia
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Abstract
Since the first outbreak of SARS-CoV-2 worldwide, research on modeling and simulation has grown, particularly to estimate the peak and end time of the pandemic which has been exceeded in some cases. This study aims to model the current virus spread with discrete event simulation, using the case of Jakarta. About 2 million of Jakarta's susceptible population was used for the the model's input which ran for a year. The data was obtained from past records and were divided into three main timelines (i.e. initial stage, large scale restriction and new normal) in order to validate the model with real cases step by step. Scenario analysis was then performed by evaluating five possible interventions such as: existing scenarios, social and health intervention, mass vaccination and hybrid intervention. The results show that the model represents real cases with a variation of less than 5% during the timeline. Furthermore, scenario analysis showed that mass vaccination, hybrid and social intervention provide the least positive cases in the system. This study recommends that hybrid intervention should be used while the vaccine is being mass produced, and the implementation of social intervention should be highlighted.
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References
Antonius, Y. 2020. Selama PSBB Jumlah Rata-rata Kendaraan Keluar Masuk Jakarta Capai 1,4 Juta Per Hari [During the large-scale social restrictions, the average number of vehicles in and out of Jakarta reached 1.4 million per day]. AKURAT.CO. Available at: https://akurat.co/news/id-1120165-read-selama-psbb-jumlah-ratarata-kendaraan-keluar-masuk-jakarta-capai-14-juta-per-hari (Accessed: 12 July 2020).
Ariawan, I., Riono, P., Farid, M.N., & Jusril, H. 2020. COVID-19 Modelling Scenarios Indonesia. Bappenas. Available at: https://perdhaki.org/wp-content/uploads/2020/03/Covid-19-modelling-27-Maret-2020-rev-18.09.pdf.
Badan Pusat Statistik Provinsi Jakarta. 2020. Jumlah Penduduk Provinsi DKI Jakarta Menurut Kelompok Umur dan Jenis Kelamin, 2018-2019 [Total Population of DKI Jakarta Province by Age Group and Gender, 2018-2019]. Badan Pusat Statistik Provinsi DKI Jakarta [BPS-Statistics of DKI Jakarta Province]. Available at: https://jakarta.bps.go.id/dynamictable/2019/09/16/58/jumlah-penduduk-provinsi-dki-jakarta-menurut-kelompok-umur-dan-jenis-kelamin-2018-.html (Accessed: 1 September 2020).
Barman, M. P., Rahman, T., Bora, K., & Borgohain, C. 2020. COVID-19 Pandemic and its Recovery Time of Patients in India: A Pilot Study. Diabetes Metabolic Syndrom: Clinical Research and Reviews, 14 (5): 1205–1211. https://dx.doi.org/10.1016%2Fj.dsx.2020.07.004.
Barratt, H., Kirwam, M., & Shantikumar, S. 2018. Epidemic Theory (Effective & Basic Reproduction Numbers, Epidemic Thresholds) & Techniques for Analysis of Infectious Disease Data (Construction & use of Epidemic Curves, Generation Numbers, Exceptional Reporting & Identification of Significant Clusters). Public Health Action Support Team (PHAST). Available at: https://www.healthknowledge.org.uk/public-health-textbook/research-methods/1a-epidemiology/epidemic-theory (Accessed: 14 August 2020).
Böhning, D., Roccetti, I., Maruoti, A., & Holling, H. 2020. Estimating the Undetected Infections in the Covid-19 Outbreak by Harnessing Capture-recapture Methods. International Journal of Infectious Diseases, 97: 197–201. https://doi.org/10.1016/j.ijid.2020.06.009.
Brailsford, S. & Hilton, N. 2001. A Comparison of Discrete Event Simulation and System Dynamics for Modelling Health Care Systems. Proceedings from ORAHS 2000, 18–39. Available at: http://eprints.soton.ac.uk/35689/1/glasgow_paper.pdf.
Bulut, C. & Kato, Y. 2020. Epidemiology of COVID-19. Turkish Journal of Medical Sciences, 50: 563–570. https://doi.org/10.3906/sag-2004-172.
Cahya, G.H. 2020. It’s meant to help: Harvard professor responds after government Dismisses Study on Undetected Coronavirus Cases. The Jakarta Post. Available at: https://www.thejakartapost.com/news/2020/02/14/its-meant-to-help-harvard-professor-responds-after-government-dismisses-study-on-undetected-coronavirus-cases.html
Castillo, R.C., Staguhn, ED., & Farber, EW. 2020. The Effect of State-level Stay-at-home Orders on COVID-19 Infection Rates. American Journal of Infection Control, 48 (8): 958-960. https://www.ajicjournal.org/article/S0196-6553(20)30314-X/fulltext.
CDC (Centers for Disease Control and Prevention). 2020a. Duration of Isolation and Precautions for Adults with COVID-19. Center for Disease Control and Prevention. Available at: https://www.cdc.gov/coronavirus/2019-ncov/hcp/duration-isolation.html (Accessed: 3 August 2020).
CDC (Centers for Disease Control and Prevention). 2020b. Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19). National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. Available at: https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html (Accessed: 1 August 2020).
CDC (Centers for Disease Control and Prevention). 2020c. People with Certain Medical Conditions. National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. Available at: https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html (Accessed: 24 August 2020).
Chumachenko D. & Chumachenko T. 2020. Intelligent Agent-Based Simulation of HIV Epidemic Process. In: Lytvynenko V., Babichev S., Wójcik W., Vynokurova O., Vyshemyrskaya S., Radetskaya S. (eds) Lecture Notes in Computational Intelligence and Decision Making. ISDMCI 2019. Advances in Intelligent Systems and Computing, 1020: 175-188. https://doi.org/10.1007/978-3-030-26474-1_13.
Chung, E. 2020. How soon should you be tested after exposure for Covid-19? Your question answered. CBC News. Available at: https://www.cbc.ca/news/health/testing-covid-19-faq-1.5593840 (Accessed: 12 August 2020).
Clark, A., Jit, M., Warren-Gash, C., Guthrie, B., Wang, H.H.X., Mercer, S.W., et al. 2020. Global, Regional, and National Estimates of the Population at Increased Risk of Severe COVID-19 due to Underlying Health Conditions in 2020: a Modelling Study. The Lancet Global Health, 8 (8). https://doi.org/10.1016/S2214-109X(20)30264-3.
CNN Indonesia 2020. Kasus Baru Corona di DKI Tak Lagi Tertinggi, Didominasi TKI [New Coronavirus Cases in DKI Jakarta Are No Longer the Highest, Dominated by Indonesian workers who work abroad]. CNN Indonesia. Available at: https://www.cnnindonesia.com/nasional/20200529113900-20-507890/kasus-baru-corona-di-dki-tak-lagi-tertinggi-didominasi-tki (Accessed: 12 August 2020).
Covid-19 Community Mobility. 2020. Covid-19 Community Mobility Reports: Indonesia. Google. Available at: https://www.google.com/covid19/mobility/
Currie, C.S.M., Fowler, J.W.,. Kotiadis, K., Monks, T., Onggo, B.S., Robertson, B.A., et al. 2020. How Simulation Modelling can Help Reduce the Impact of COVID-19. Journal of Simulation, 14 (2): 1–15. https://doi.org/10.1080/17477778.2020.1751570.
Damarjati, D. 2020. Pakar: Physical Distancing Turunkan Penularan Corona, tapi Belum Cukup [Expert: Physical Distancing Reduces Corona Transmission, but Not Enough]. detikNews. Available at: https://news.detik.com/berita/d-4979753/pakar-physical-distancing-turunkan-penularan-corona-tapi-belum-cukup/2 (Accessed: 2 September 2020).
Del Valle, S.Y., Hyman, J.M., Hethcote, H., & Eubank, S.G. 2007. Mixing Patterns Between Age Groups in Social Networks. Social Networks, 29 (4): 539–554. https://doi.org/10.1016/j.socnet.2007.04.005
Detikcom. 2020. Kasus Corona di DKI Tembus 7.000, 19% Berasal dari Luar Jakarta. detikNews. Available at: https://news.detik.com/berita/d-5033541/kasus-corona-di-dki-tembus-7000-19-berasal-dari-luar-jakarta (Accessed: 3 August 2020).
Dewi, F. S. 2020. Anjuran Work From Home, Lalu Lintas Tol Jasa Marga Tetap Normal. Bisnis Indonesia. Available at: https://ekonomi.bisnis.com/read/20200317/45/1214434/anjuran-work-from-home-lalu-lintas-tol-jasa-marga-tetap-normal (Accessed: 12 August 2020).
Dietz, K. 1988. The First Epidemic Model: a Historical Note on PD En’ko. Australian Journal of Statistics, 30 (1): 56–65. https://doi.org/10.1111/j.1467-842X.1988.tb00464.x.
van den Driessche, P. 2017. Reproduction Numbers of Infectious Disease Models. Infectious Disease Modelling, 2 (3): 288–303. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002118/.
Erina, R. 2020. Analis AS: Kesalahan Penanganan Virus Corona Di Indonesia Telah Mengubah Wabah Menjadi Musibah. Kantor Berita Politik. RMOL.ID. Available at: https://dunia.rmol.id/read/2020/05/04/433270/analis-as-kesalahan-penanganan-virus-corona-di-indonesia-telah-mengubah-wabah-menjadi-musibahâ€.
Fadly, F. & Sari, E. 2020. An Approach to Measure the Death Impact of Covid-19 in Jakarta using Autoregressive Integrated Moving Average (ARIMA). Unnes Journal of Public Health, 9 (2): 108–116. https://doi.org/10.15294/ujph.v9i2.38460.
Falasca, L., Nardacci, R., Colombo, D., Lalle, E., Caro, AD., Nicastri, E., Antinori, A., Petrosillo, N., Marchioni, L., Biava, G., et al. 2020. Postmortem Findings in Italian Patients With COVID-19: A Descriptive Full Autopsy Study of Cases with and Without Comorbidities. Journal of Infectious Disease, 222 (11): 1807-1815. https://doi.org/10.1093/infdis/jiaa578.
Fauziah, A. 2020. Sempat Gagal Napas Hingga Dirawat Selama 75 Hari di RS, Pria 48 Tahun Berhasil Sembuh dari Covid-19. TribunMataram.com. Available at: https://mataram.tribunnews.com/amp/2020/06/18/sempat-gagal-napas-hingga-dirawat-selama-75-hari-di-rs-pria-48-tahun-berhasil-sembuh-dari-covid-19?page=2 (Accessed: 14 August 2020).
Ferdiaz, N. Y. 2020. Usai BNPB Sebut Ada Ketidaksesuaian Data, Kini Penelitian Gabungan Ungkap Ada 32 Ribu Kasus Positif Virus Corona di DKI Jakarta. Kompas Gramedia. Available at: https://health.grid.id/read/352101528/usai-bnpb-sebut-ada-ketidaksesuaian-data-kini-penelitian-gabungan-ungkap-ada-32-ribu-kasus-positif-virus-corona-di-dki-jakarta?page=all (Accessed: 21 August 2020).
Fornel, D. 2020. COVID-19 Genetic PCR Tests Give False Negative Results if Used Too Early. Imaging Technology News (itn). Available at: https://www.itnonline.com/content/covid-19-genetic-pcr-tests-give-false-negative-results-if-used-too-early (Accessed: 6 September 2020).
Gallagher, J. 2020. Coronavirus: How long does it take to recover?. BBC News. Available at: https://www.bbc.com/news/health-52301633 (Accessed: 6 July 2020).
Global Health Security Team. 2020. Coronavirus world round-up: Beijing reports a decline in cases, but travel restrictions placed on 500,000. Telegraph Media Group. Available at: https://www.telegraph.co.uk/news/2020/06/18/coronavirus-world-round-up-beijing-reports-decline-cases-travel/ (Accessed: 1 August 2020).
Government of Jakarta Capital Special Region. 2020. Data Monitoring of Covid in Jakarta. Posko Tim Tanggap Covid-19 Dinas Kesehatan DKI Jakarta. Available at: https://corona.jakarta.go.id/id/data-pemantauan (Accessed: 12 August 2020).
Government of Riau Province. 2020. Pasien Covid-19 Rata-rata Dirawat 7-10 Hari Sebelum Dinyatakan Sembuh. mediacenter.riau.go.id. Available at: https://mediacenter.riau.go.id/read/53166/pasien-covid-19-rata-rata-dirawat-7-10-hari-s.html (Accessed: 2 July 2020).
Hamonangan, J. (ed). 2019. Prevalensi Hipertensi dan Diabetes di DKI Jakarta Tergolong Tinggi. wartakota.tribunnews.com. Available at: https://wartakota.tribunnews.com/2019/10/03/prevalensi-hipertensi-dan-diabetes-di-dki-jakarta-tergolong-tinggi. (Accessed: 4 September 2020).
Hao, X., Cheng, S., Wu, D., Wu, T., Lin, X., & Wang, C. 2020. Reconstruction of the Full Transmission Dynamics of COVID-19 in Wuhan. Nature, 584 (7821): 420–424. https://pubmed.ncbi.nlm.nih.gov/32674112/.
Harvard Medical School. 2020. If you’ve been exposed to the coronavirus. Harvard Health Publishing. Available at: https://www.health.harvard.edu/diseases-and-conditions/if-youve-been-exposed-to-the-coronavirus (Accessed: 6 September 2020).
Hauzah, H &Saubani, A., 2020. IDI: RS Rujukan Covid Penuh, Bulan Depan Kelebihan Kapasitas. https://republika.co.id/berita/qexrvl409/idi-rs-rujukan-covid-penuh-bulan-depan-kelebihan-kapasitas?utm_source=izooto&utm_medium=push_notifications&utm_campaign=Kampanye%20Nasional%20-%20All&utm_content=&utm_term=
Hethcote, H.W. 2000. The Mathematics of Infectious Diseases. Society for Industrial and Applied Mathematics, 42 (4): 599–653. https://doi.org/10.1137/S0036144500371907.
Hilton, T. 2020. Coronavirus: Up to 80 Percent of People can’t Catch COVID-19, Says Leading Scientist. Al Arabiya.
Ihsanudin & Erdianto, K. (ed). 2020. Fakta Lengkap Kasus Pertama Virus Corona di Indonesia. Kompas. Available at: https://nasional.kompas.com/read/2020/03/03/06314981/fakta-lengkap-kasus-pertama-virus-corona-di-indonesia?page=all (Accessed: 1 December 2020).
Jones, J.H. 2020. Notes on Ro. web.stanford.edu. Available at: https://web.stanford.edu/~jhj1/teachingdocs/Jones-on-R0.pdf (Accessed: 30 August 2020).
Junita, N, 2020. 172 Rumah Sakit dan 1.200 Tempat Tidur Disiapkan untuk Pasien Covid-19 di Jakarta. Accessed on August 12th, 2020. https://jakarta.bisnis.com/read/20200507/77/1237537/172-rumah-sakit-dan-1.200-tempat-tidur-disiapkan-untuk-pasien-covid-19-di-jakarta
Kiran, D. R. 2019. Production Planning and Control: a Comprehensive Approach. Butterworth-Heinemann.: Elsevier. https://doi.org/10.1016/C2018-0-03856-6.
Lewnard, J.A., & Lo, N.C. 2020. Scientific and Ethical Basis for Social Distancing Interventions Against COVID-19. The Lancet Infectious Diseases, 20 (6): 631-633. https://doi.org/10.1016/S1473-3099(20)30190-0.
Manurung, M.Y., & Hantoro, J. 2020. Diabetes Jadi Komorbid Utama Pasien Positif Covid-19 di Jakarta. Tempo. Available at: https://metro.tempo.co/read/1372840/diabetes-jadi-komorbid-utama-pasien-positif-covid-19-di-jakarta/full&view=ok (Accessed: 2 September 2020).
Manafe, D. 2020. Lama Pasien Covid-19 Dirawat Rata-rata Dua Minggu. Beritasatu.com. Available at: https://www.beritasatu.com/yudo-dahono/nasional/651499/lama-pasien-covid19-dirawat-ratarata-dua-minggu (Accessed: 2 July 2020).
Miller, G., Randolph, S. & Patterson, J. E. 2008. Responding to Simulated Pandemic Influenza in San Antonio, Texas. Infection Control & Hospital Epidemiology, 29 (4): 320–326. https://doi.org/10.1086/529212.
National Covid-19 Task Force Republic of Indonesia. 2020a. Data Covid-19. Available at: https://covid19.go.id/peta-sebaran (Accessed: 18 August 2020).
National Covid-19 Taskforce Republic of Indonesia. 2020b. Pedoman Penanganan Cepat Medis dan Kesehatan Masyarakat Covid-19 di Indonesia (Guideline of Medical and Public Health Fast Response on Covid-19 in Indonesia. Kementerian Kesehatan Republik Indonesia. Available at: https://covid19.kemkes.go.id/protokol-covid-19/pedoman-penanganan-cepat-medis-dan-kesehatan-masyarakat-covid-19-di-indonesia/#.X1AKyYsxU2w (Accessed: 12 August 2020).
Nugraheni, D. E. & Kuwado, F. J. 2020. Jumlah Warga Indonesia Bersiko Terjangkit Corona Capai 700.000 Orang. Kompas. Available at: https://nasional.kompas.com/read/2020/03/20/20014681/jumlah-warga-indonesia-berisiko-terjangkit-corona-capai-700000-orang?page=all (Accessed: 24 August 2020).
Nuraini, N., Khairudin, K. & Apri, M. 2020. Modeling Simulation of COVID-19 in Indonesia based on Early Endemic Data. Communication in Biomathematical Sciences, 3 (1): 1–8. http://journals.itb.ac.id/index.php/cbms/article/view/13395.
Permana, Y. H. & Sahadewo, G. 2020. A Tale of Two Peaks: Predicting the Peak of Covid-19 Infections in Indonesia. Preprint. https://doi.org/10.13140/RG.2.2.29574.80966.
Qin, J., You, C., Lin, Q., Hu, T., Yu, S., & Zhou, X.H. 2020. Estimation of incubation period distribution of COVID-19 using disease onset forward time: A Novel Cross-sectional and Forward Follow-up Study. Science Advances, 6 (33): 1–16. https://doi.org/10.1126/sciadv.abc1202.
Rantung, F. 2020. Erick Thohir: 66% Rakyat Indonesia Mau Disuntik Vaksin Covid-19. Oke Zone. Available at: https://economy.okezone.com/read/2020/12/01/320/2319715/erick-thohir-66-rakyat-indonesia-mau-disuntik-vaksin-covid-19 (Accessed: 1 December 2020).
Rees, E.M., Nightingale, E.S., Jafari, Y., Waterlow, N.R., Liffrord, S., Pearson, C.A.B., et al. 2020. COVID-19 Length of Hospital Stay: a Systematic Review and Data Synthesis. BMC Medicine, 18 (1). https://doi.org/10.1186/s12916-020-01726-3.
Rothman, K.J., Greenland, S., & Lash, T.L. 2008. Modern Epidemiology. USA: Lippincott Williams & Wilkins.
Setyawan, F.E.B. & Lestari, R. 2020. Challenges of Stay at Home Policy Implementation during the Coronavirus (Covid-19) Pandemic in Indonesia. Jurnal Administrasi Kesehatan Indonesia, 8: 15-20. https://e-journal.unair.ac.id/JAKI/article/view/18789
Shereen, M.A., Khan, S., Kazmi, A., Bashir, N., & Siddique, R. 2020. COVID-19 Infection: Origin, Transmission, and Characteristics of Human Coronaviruses. Journal of Advanced Research, 24: 91-98. https://doi.org/10.1016/j.jare.2020.03.005.
Singh, J.A. & Upshur, R.E.G. 2020. The Granting of Emergency use Designation to COVID-19 Candidate Vaccines: Implications for COVID-19 Vaccine Trials. The Lancet Infectious Disease. https://doi.org/10.1016/S1473-3099(20)30923-3.
The Government of Jakarta. 2020. Dampak Covid-19 terhadap Tingkat Kemacetan di DKI Jakarta. Available at: https://datastudio.google.com/u/0/reporting/3ef9f98e-8d42-47fa-a0e2-9f84c1f45ad9/page/LAFMB?s=hHvIzIXDeNE (Accessed: 24 August 2020).
Triatmojo, D. & Simanjuntak, J. (ed). 2020. Jumlah Kendaraan Saat ini Sudah Mendekati Kondisi Sebelum Pandemi. tribunnews.com. Available at: https://www.tribunnews.com/corona/2020/07/02/kadishub-dki-jumlah-kendaraan-saat-ini-sudah-mendekati-kondisi-sebelum-pandemi (Accessed: 2 September 2020).
UNICEF. 2020. Mobility Insight. UNICEF Indonesia. Available at: https://www.unicef.org/indonesia/coronavirus/stories/mobility-insights (Accessed: 2 September 2020).
Wahyudi, N.A., 2020. Gawat, Pasien Covid-19 di Jakarta Antre Tempat Tidur di Rumah Sakit Rujukan. Accessed on August 12th, 2020. https://jakarta.bisnis.com/read/20200812/77/1278186/gawat-pasien-covid-19-di-jakarta-antre-tempat-tidur-di-rumah-sakit-rujukan
WHO Indonesia. 2020. Media Statement: Knowing the Risks for COVID-19. WHO Indonesia media. Available at: https://www.who.int/indonesia/news/detail/08-03-2020-knowing-the-risk-for-covid-19
World Health Organization. 2020a. Coronavirus: Symptoms. WHO International. Available at: https://www.who.int/health-topics/coronavirus#tab=tab_3 (Accessed: 4 September 2020).
World Health Organization. 2020b. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). WHO International. Available at: https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf.
Yulida, Y. & Karim, M.A. 2020. Pemodelan Matematika Penyebaran Covid-19 Di Provinsi Kalimantan Selatan. Media Bina Ilmiah, 14 (10): 3257–3264. https://ejurnal.binawakya.or.id/index.php/MBI/article/view/572