Kencur Supplementation for Attenuating Exercise-Induced Muscle Damage and Delayed-Onset Muscle Soreness

Roy Januardi Irawan(1), Soni Sulistyarto(2), Nanda Rimawati(3),


(1) Universitas Negeri Surabaya
(2) Universitas Negeri Surabaya
(3) Universitas Negeri Surabaya

Abstract

Delayed Onset Muscle Soreness (DOMS) is a pain that occurs after uncustomized eccentric exercise and can happen to anyone, both those who are athletes and other individuals. DOMS is usually felt 24-72 hours after exercise or activities that use eccentric movements, which interfere with the athlete’s training activities and other individuals’ daily activities. This study aimed to determine the effectiveness of kencur extract supplementation (kaempferia galanga linn) on DOMS and creatine kinase (CK) plasma levels after eccentric exercise. This research is quasi-experimental, using a randomized control group design as the design in this study. Research subjects (n = 28) were randomly divided into 2 groups, namely the kencur extract group (200 mg/day) and the placebo group (corn flour). The supplementation process in both groups was carried out for 5 days (3 days before and 2 days after) the eccentric exercise. DOMS pain (VAS) and blood samples (CK plasma) were taken 24 hours (pre) and 48 hours (post) after eccentric exercise. The destructive drill uses the 5 x 20 Eccentric depth jump drill. The data obtained in the form of changes in DOMS pain and CK plasma were then analyzed using ANOVA with sig. <0.005. Supplementation of galingale extract was effective in reducing DOMS pain with p = 0.008 (<0.05) and CK plasma value p = 0.000 (<0.05) compared to placebo after eccentric exercise. Supplementation of galingale extract (Kaempferia Galanga Linn) for 5 days is effective as an effort to reduce the risk of DOMS pain sensation and reduce the increase in muscle damage with CK as a marker after eccentric exercise.

Keywords

Kencur; muscle damage; supplement; nutrition; eccentric exercise

Full Text:

PDF

References

Akinci, B., Yazgan, Y.Z., & Altinoluk, T., 2020. The Effectiveness of Three Different Recovery Methods on Blood Lactate, Acute Muscle Performance, and Delayed-Onset Muscle Soreness: A Randomized Comparative Study. The Journal of Sports Medicine and Physical Fitness, 60(3).

Ali, H., Yesmin, R., Satter, M.A., Habib, R., & Yeasmin, T., 2018. Antioxidant and Antineoplastic Activities of Methanolic Extract of Kaempferia Galanga Linn. Rhizome against Ehrlich Ascites Carcinoma Cells. Journal of King Saud University - Science, 30(3), pp.386–92.

Amalraj, A., Divya, C., & Gopi, S., 2020. The Effects of Bioavailable Curcumin (Cureit) on Delayed Onset Muscle Soreness Induced By Eccentric Continuous Exercise: A Randomized, Placebo-Controlled, Double-Blind Clinical Study. Journal of Medicinal Food, 23(5), pp.545–53.

Angelopoulos, P., Diakoronas, A., Panagiotopoulos, D., Tsekoura, M., Xaplanteri, P., Koumoundourou, D., Saki, F., Billis, E., Tsepis, E., & Fousekis, K., 2022. Cold-Water Immersion and Sports Massage Can Improve Pain Sensation but Not Functionality in Athletes with Delayed Onset Muscle Soreness. Healthcare, 10(12), pp.2449.

Anggarani, M.A., & Irawan, R.J., 2020. Antioxidant Potential of Madura Knife Scallop (Solen Sp) Extract as a Prevention of Oxidative Stress. Jurnal Kesehatan Masyarakat, 15(3), pp. 382–89.

Baird, M.F., Graham, S.M., Baker, J.S., & Bickerstaff, G.F., 2012. Creatine-Kinase- and Exercise-Related Muscle Damage Implications for Muscle Performance and Recovery. Journal of Nutrition and Metabolism, 2012, pp.1–13.

Banwo, K., Olojede, A.O., Adesulu-Dahunsi, A.T., Verma, D.K., Thakur, M., Tripathy, S., Singh, S., Patel, A.R., Gupta, A.K., Aguilar, C.N., & Utama, G.L., 2021. Functional Importance of Bioactive Compounds of Foods with Potential Health Benefits: A Review on Recent Trends. Food Bioscience, 43, pp.101320.

Chang, W.-D., Chang, N.-J., Lin, H.-Y., & Wu, J.-H., 2020. Effects of Acupuncture on Delayed-Onset Muscle Soreness: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine, 2020, pp.1–11.

Chang, W.-D., Lin, H.-Y., Chang, N.-J., & Wu, J.-H., 2021. Effects of 830 Nm Light-Emitting Diode Therapy on Delayed-Onset Muscle Soreness. Evidence-Based Complementary and Alternative Medicine, 2021, pp.1–7.

Connolly, D.A.J., Sayers, S.P., & Mchugh, M.P., 2003. Treatment and Prevention of Delayed Onset Muscle Soreness. Journal of Strength and Conditioning Research, 17.

da Silva, W., Machado, A.S., Souza, M.A., Mello-Carpes, P.B., Carpes, F.P., 2018. Effect of Green Tea Extract Supplementation on Exercise-Induced Delayed Onset Muscle Soreness and Muscular Damage. Physiology & Behavior, 194, pp.77–82.

Davis, H.L., Alabed, S., & Chico, T.J.A., 2020. Effect of Sports Massage on Performance and Recovery: A Systematic Review and Meta-Analysis. BMJ Open Sport & Exercise Medicine, 6(1), pp.e000614.

Fedewa, M.V., Spencer, S.O., Williams, T.D., Becker, Z.E., & Fuqua, C.A., 2019. Effect of Branched-Chain Amino Acid Supplementation on Muscle Soreness Following Exercise: A Meta-Analysis. International Journal for Vitamin and Nutrition Research, 89(5–6), pp.348–56.

Howatson, G., McHugh, M.P., Hill, J.A., Brouner, J., Jewell, A.P., van Someren, K.A., Shave, R.E., & Howatson, S.A., 2010. Influence of Tart Cherry Juice on Indices of Recovery Following Marathon Running. Scandinavian Journal of Medicine & Science in Sports, 20(6), pp.843–52.

Ichwan, S.J.A., Husin, A., Suriyah, W.H., Lestari, W., Omar, M.N., & Kasmuri, A.R., 2019. Anti-Neoplastic Potential of Ethyl-p-Methoxycinnamate of Kaempferia Galanga on Oral Cancer Cell Lines. Materials Today: Proceedings, 16, pp.2115–21.

Irawan, R.J., Sulistyarto, S., & Rimawati, N., 2022. Supplementation Of Kencur (Kaempferia Galanga Linn) Extract on Malondealdehyde (MDA) and IL-6 Plasma Levels Post Aerobic Training Activity. Amerta Nutrition, 6(1SP), pp.140–45.

Jenkins, N.D.M., Housh, T.J., Johnson, G.O., Traylor, D.A., Bergstrom, H.C., Cochrane, K.C., Lewis Jr, R.W., Schmidt, R.J., & Cramer, J.T., 2013. The Effects of Anatabine on Non-Invasive Indicators of Muscle Damage: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Journal of the International Society of Sports Nutrition, 10(1).

Khairullah, A.R., Solikhah, T.I., Ansori, A.N.M., Hanisia, R.H., Puspitarani, G.A., Fadholly, A., & Ramandinianto, S.C., 2021. Medicinal Importance of Kaempferia Galanga L. (Zingiberaceae): A Comprehensive Review. Journal of Herbmed Pharmacology, 10(3), pp.281–88.

Triplett, N.T., Haines, T.L., Skinner, J.W., Fairbrother, K.R., & McBride, J.M.,Kirby, Tyler J. et al. 2012. “Effect of Leucine Supplementation on Indices of Muscle Damage Following Drop Jumps and Resistance Exercise.” Amino Acids 42(5): 1987–96.

Kodesh, E., Sirkis-Gork, A., Mankovsky-Arnold, T., Shamay-Tsoory, S., & Weissman-Fogel, I., 2022. Susceptibility to Movement-Evoked Pain Following Resistance Exercise. Plos One, 17(7), pp.e0271336.

Koeda, S., Yoshikawa, T., Sato, C., Sumigawa, K., & Yamada, J., 2019. Ultrasound Irradiation before High-Load Exercise Reduces Muscle Rigidity Associated with Delayed-Onset Muscle Soreness. Journal of Physical Therapy Science, 31(11), pp.922–24.

Konrad, A., Kasahara, K., Yoshida, R., Yahata, K., Sato, S., Murakami, Y., Aizawa, K., & Nakamura, M., 2022. Relationship between Eccentric-Exercise-Induced Loss in Muscle Function to Muscle Soreness and Tissue Hardness. Healthcare, 10(1), pp.96.

Kumar, A., 2020. Phytochemistry, Pharmacological Activities and Uses of Traditional Medicinal Plant Kaempferia Galanga L. – An Overview. Journal of Ethnopharmacology, 253, pp.112667.

Lamb, K.L., Ranchordas, M.K., Johnson, E., Denning, J., Downing, F., & Lynn, A., 2019. No Effect of Tart Cherry Juice or Pomegranate Juice on Recovery from Exercise-Induced Muscle Damage in Non-Resistance Trained Men. Nutrients, 11(7), pp.1593.

Lewis, P.B., Ruby, D., & Bush-Joseph, C.A., 2012. Muscle Soreness and Delayed-Onset Muscle Soreness. Clinics in Sports Medicine, 31(2), pp.255–62.

Lorensia, A., Suryadinata, R.V., & Mahfidz, I.K., 2022. Effects of Dietary Antioxidant Intake on Lung Functions in Construction Workers in Surabaya. Jurnal Kesehatan Masyarakat, 18(1), pp.20–30.

Lund, H., Vestergaard-Poulsen, P., Kanstrup, I.L., & Sejrsen P., 2007. The Effect of Passive Stretching on Delayed Onset Muscle Soreness, and Other Detrimental Effects Following Eccentric Exercise. Scandinavian Journal of Medicine & Science in Sports, 8(4), pp.216–21.

Matsumura, M.D., Zavorsky, G.S., & Smoliga, J.M., 2015. The Effects of Pre-Exercise Ginger Supplementation on Muscle Damage and Delayed Onset Muscle Soreness. Phytotherapy Research, 29(6), pp.887–93.

McFarlin, B.K., Venable, A.S., Henning, A.L., Sampson, J.N.B., Pennel, K., Vingren, J.L., & Hill, D.W., 2016. Reduced Inflammatory and Muscle Damage Biomarkers Following Oral Supplementation with Bioavailable Curcumin. BBA Clinical, 5, pp.72–78.

Mickleborough, T.D., Sinex, J.A., Platt, D., Chapman, R.F., & Hirt, M., 2015. The Effects PCSO-524®, a Patented Marine Oil Lipid and Omega-3 PUFA Blend Derived from the New Zealand Green Lipped Mussel ( Perna Canaliculus ), on Indirect Markers of Muscle Damage and Inflammation after Muscle Damaging Exercise in Untrained Men: A Randomized, Placebo Controlled Trial. Journal of the International Society of Sports Nutrition, 12(1).

Nakhostin-Roohi, B., Moradlou, A.N., Hamidabad, S.M., & Ghanivand, B., 2016. The Effect of Curcumin Supplementation on Selected Markers of Delayed Onset Muscle Soreness (DOMS). Annals of Applied Sport Science, 4(2), pp.25–31.

Nogueira, N.M., Felappi, C.J., Lima, C.S., & Medeiros, D.M., 2020. Effects of Local Cryotherapy for Recovery of Delayed Onset Muscle Soreness and Strength Following Exercise-Induced Muscle Damage: Systematic Review and Meta-Analysis. Sport Sciences for Health, 16(1), pp.1–11.

Pumpa, K.L., Fallon, K.E., Bensoussan, A., & Papalia, S., 2011. The Effects of Lyprinol® on Delayed Onset Muscle Soreness and Muscle Damage in Well Trained Athletes: A Double-Blind Randomised Controlled Trial. Complementary Therapies in Medicine, 19(6), pp.311–18.

Ridtitid, W., Sae-wong, C., Reanmongkol, W., & Wongnawa, M., 2008. Antinociceptive Activity of the Methanolic Extract of Kaempferia Galanga Linn. in Experimental Animals. Journal of Ethnopharmacology, 118(2), pp. 225–30.

Ringuet, M.T., Hunne, B., Lenz, M., Bravo, D.M., & Furness, J.B., 2021. Analysis of Bioavailability and Induction of Glutathione Peroxidase by Dietary Nanoelemental, Organic and Inorganic Selenium. Nutrients, 13(4), pp.1073.

Rynders, C.A., Weltman, J.Y., Rynders, S.D., Patrie, J., McKnight, J., Katch, F., & Weltman, J.H.A., 2014. Effect of an Herbal/Botanical Supplement on Recovery from Delayed Onset Muscle Soreness: A Randomized Placebo-Controlled Trial. Journal of the International Society of Sports Nutrition, 11(1).

Sagita, M.B., Turchan, A., Utomo, B., Fauzi, A.A., & Fauziah, D., 2022. Expression Malondialdehyde (MDA) of Brain after Injury with the Extract of Kencur (Kaempferia Galanga L). International Journal of Health & Medical Sciences, 5(1), pp.114–21.

Samodra, G., & Febrina, D., 2020. The Comparison Between Anti-Inflammatory Effects of Ethanol Extract from Kaempferia Galanga L. and Diclofenac Sodium Induced by Carrageenan. Proceedings of the 1st International Conference on Community Health (ICCH 2019). Paris, France: Atlantis Press.

Shi, Y., Shu, H., Wang, X., Zhao, H., Lu, C., Lu, A., & He, X., 2020. Potential Advantages of Bioactive Compounds Extracted From Traditional Chinese Medicine to Inhibit Bone Destructions in Rheumatoid Arthritis. Frontiers in Pharmacology, 11.

Sonkodi, B., 2021. Delayed Onset Muscle Soreness (DOMS): The Repeated Bout Effect and Chemotherapy-Induced Axonopathy May Help Explain the Dying-Back Mechanism in Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases. Brain Sciences, 11(1), pp.108.

Sulistyarto, S., Irawan, R., Kumaat, N.A., & Rimawati, N., 2022. Correlation of Delayed Onset Muscle Soreness and Inflammation Post-Exercise Induced Muscle Damage. Open Access Macedonian Journal of Medical Sciences, 10(A), pp.1688–94.

Torre, M.F., Martinez-Ferran, M., Vallecillo, N., Jiménez, S.L., Romero-Morales, C., Pareja-Galeano, H., 2021. Supplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review. Antioxidants, 10(2), pp.279.

Wang, F.-L., Luo, J.-G., Wang, X.-B., & Kong, L.-Y., 2013. A Pair of Sulfonated Diarylheptanoid Epimers from Kaempferia Galanga. Chinese Journal of Natural Medicines, 11(2), pp.171–76.

Yang, X., Ji, H., Feng, Y., Yu, J., & Liu, A., 2018. Structural Characterization and Antitumor Activity of Polysaccharides from Kaempferia Galanga L. Oxidative Medicine and Cellular Longevity, 2018, pp.1–10.

Yao, F., Huang, Y., Wang, Y., & He, X., 2018. Anti-Inflammatory Diarylheptanoids and Phenolics from the Rhizomes of Kencur (Kaempferia Galanga L.). Industrial Crops and Products, 125, pp.454–61.

Yoshida, R., Nakamura, M., & Ikegami, R., 2022. The Effect of Single Bout Treatment of Heat or Cold Intervention on Delayed Onset Muscle Soreness Induced by Eccentric Contraction. Healthcare, 10(12), pp.2556.

Zulaini, N., Harahap, S., Siregar, N.S., & Zulfahri., 2021. Effect Stretching and Recovery on Delayed Onset Muscle Soreness (DOMS) After Exercise. Journal of Physics: Conference Series, 1811(1), pp.012113.

Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.