Rheumatoid Factor, C-Reactive Protein, Erythrocyte Sedimentation Rate Responses on Brisk Walking in Rheumatoid Arthritis Women
(1) Faculty of Sports Science, Universitas Negeri Semarang
(2) Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang
(3) College of Education, Mindanao State University-Iligan Institute of Technology, Iligan
(4) College of Physical Education and Health, East China Normal University
(5) Faculty of Sports Science, Universitas Negeri Semarang
(6) Faculty of Sports Science, Universitas Negeri Semarang
(7) Faculty of Sports Science, Universitas Negeri Semarang, INDONESIA
(8) Faculty of Public Health, Universitas Muhammadiyah Semarang
Abstract
Modified Physical Exercise Program (MPEP) is necessary for people with rheumatoid arthritis (RA). This study aims to investigate the effects of MPEP on the Rheumatoid Factor (RF), C-Reactive Protein (CRP), and Erythrocyte Sedimentation Rate (ESR); to evaluate the correlation between CRP-ESR. This is a quasi-experimental study. Ten RA women who were recommended by the Dukuhseti PHC have participated. The procedure is ethically approved. The venous blood samples were used to measure the dependent variables. Eight-teen sessions of MPEP were done. A two-tailed paired t-test to elucidate the differences in pre-post data; the bivariate Pearson correlation test for CRP-ESR. The RF increased significantly (pre: 19,40±2,46 and post: 22,40±2,41). CRP increased (pre: 0,30±0,07 and post: 0,37±0,06; p< 0,05). The change in ESR is not significant. There is a strong-positive, significant correlation (r: 0,831) between CRP-ESR. We concluded that MPEP is not able to lower the RA parameters, and there is a positive feedback correlation between CRP-ESR.
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Azeez, M., Clancy, C., O’Dwyer, T., Lahiff, C., Wilson, F., & Cunnane, G. (2020). Benefits of exercise in patients with rheumatoid arthritis: a randomized controlled trial of a patient-specific exercise programme. Clinical Rheumatology, 39(6), 1783–1792. https://doi.org/10.1007/s10067-020-04937-4
Bağlan Yentur, S., Ercan, Z., Deniz, G., Karataş, A., Gür, M., Alkan, G., & Serdar Koca, S. (2023). Effects of acute aerobic exercise on brain-derived neurotrophic factor level in rheumatoid arthritis patients. Archives of Rheumatology, 38(x), i–viii. https://doi.org/10.46497/ArchRheumatol.2023.9599
Balchin, C., Tan, A. L., Golding, J., Bissell, L.-A., Wilson, O. J., McKenna, J., & Stavropoulos-Kalinoglou, A. (2022). Acute effects of exercise on pain symptoms, clinical inflammatory markers and inflammatory cytokines in people with rheumatoid arthritis: a systematic literature review. Therapeutic Advances in Musculoskeletal Disease, 14, 1759720X221114104. https://doi.org/10.1177/1759720X221114104
Bartlett, D. B., Willis, L. H., Slentz, C. A., Hoselton, A., Kelly, L., Huebner, J. L., Kraus, V. B., Moss, J., Muehlbauer, M. J., Spielmann, G., Kraus, W. E., Lord, J. M., & Huffman, K. M. (2018). Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Research & Therapy, 20(1), 127. https://doi.org/10.1186/s13075-018-1624-x
Bray, C., Bell, L. N., Liang, H., Haykal, R., Kaiksow, F., Mazza, J. J., & Yale, S. H. (2016). Erythrocyte Sedimentation Rate and C-reactive Protein Measurements and Their Relevance in Clinical Medicine. WMJ : Official Publication of the State Medical Society of Wisconsin, 115(6), 317–321.
Bremander, A., Malm, K., Andersson, M. L., & group, on behalf of the B. study. (2020). Physical activity in established rheumatoid arthritis and variables associated with maintenance of physical activity over a seven-year period – a longitudinal observational study. BMC Rheumatology, 4(1), 53. https://doi.org/10.1186/s41927-020-00151-6
Dessie, G., Tadesse, Y., Demelash, B., Genet, S., Malik, T., & Dejenie, T. A. (2021). Evaluation of c-reactive protein and associated factors among patients suffering from rheumatoid arthritis at tikur anbessa specialized hospital, Addis Ababa, Ethiopia. Open Access Rheumatology: Research and Reviews, 13, 247–255. https://doi.org/10.2147/OARRR.S325308
Di Giuseppe, D., Bottai, M., Askling, J., & Wolk, A. (2015). Physical activity and risk of rheumatoid arthritis in women: A population-based prospective study. Arthritis Research and Therapy, 17(1). https://doi.org/10.1186/s13075-015-0560-2
Hashemi, R., Majidi, A., Motamed, H., Amini, A., Najari, F., & Tabatabaey, A. (2015). Erythrocyte Sedimentation Rate Measurement Using as a Rapid Alternative to the Westergren Method. Emergency, 3(2), 50–53. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614602/#
Hidayat, R., Bagus Putu Putra Suryana, Linda Kurniaty Wijaya, Anna Ariane, Rakhma Yanti Hellmi, Endy Adnan, & Sumariyono. (2021). Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Rheumatoid Arthritis. Indonesian Journal of Rheumatology, 13(1), 322–443. https://doi.org/10.37275/ijr.v13i1.173
Hu, H., Xu, A., Gao, C., Wang, Z., & Wu, X. (2021). The effect of physical exercise on rheumatoid arthritis: An overview of systematic reviews and meta-analysis. Journal of Advanced Nursing, 77(2), 506–522. https://doi.org/https://doi.org/10.1111/jan.14574
Ingegnoli, F., Castelli, R., & Gualtierotti, R. (2013). Rheumatoid factors: clinical applications. Disease Markers, 727–734. https://doi.org/https://doi.org/10.1155/2013/726598
Khoja, S. S., Almeida, G. J., Wasko, M. C., Terhorst, L., & Piva, S. R. (2016). Association of Light-Intensity Physical Activity With Lower Cardiovascular Disease Risk Burden in Rheumatoid Arthritis. Arthritis Care & Research, 68(4), 424–431. https://doi.org/https://doi.org/10.1002/acr.22711
Kotulska, A., Kopeć-Mędrek, M., Grosicka, A., Kubicka, M., & Kucharz, E. J. (2015). Correlation between erythrocyte sedimentation rate and C-reactive protein level in patients with rheumatic diseases. Reumatologia, 53(5), 243–246. https://doi.org/10.5114/reum.2015.55825
Lapić, I., Padoan, A., Bozzato, D., & Plebani, M. (2020). Erythrocyte Sedimentation Rate and C-Reactive Protein in Acute Inflammation: Meta-Analysis of Diagnostic Accuracy Studies. American Journal of Clinical Pathology, 153(1), 14–29. https://doi.org/10.1093/ajcp/aqz142
Markanday, A. (2015). Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infectious Diseases, 2(3), ofv098. https://doi.org/10.1093/ofid/ofv098
Marni, & Husna, P. H. (2023). Physical Domain of Quality of Life in Premenopause and Post Menopause Women in Central of Java. Kemas, 19(2), 319–332. https://doi.org/10.15294/kemas.v19i2.45253
Padjen, I., Crnogaj, M. R., & Anić, B. (2020). Conventional disease-modifying agents in rheumatoid arthritis - a review of their current use and role in treatment algorithms. Reumatologia, 58(6), 390–400. https://doi.org/doi: 10.5114/reum.2020.101400
Prihanti, G. S., Wilyani, D., Isnaini, F., Ailani, A. F., Humaira, A. A., Kurniawan, I. K., Rahayu, K. P., Hadiyanti, L. A., & Santoso, S. R. (2022). Community Awareness for Screening Non-Communicable Diseases. Kemas, 18(2), 181–192. https://doi.org/10.15294/kemas.v18i2.35039
Safiri, S., Kolahi, A. A., Hoy, D., Smith, E., Bettampadi, D., Mansournia, M. A., Almasi-Hashiani, A., Ashrafi-Asgarabad, A., Moradi-Lakeh, M., Qorbani, M., Collins, G., Woolf, A. D., March, L., & Cross, M. (2019). Global, regional and national burden of rheumatoid arthritis 19902017: a systematic analysis of the Global Burden of Disease study 2017. Annals of the Rheumatic Diseases, 78(11), 1463–1471. https://doi.org/10.1136/annrheumdis-2019-215920
Senara, S. H., Abdel Wahed, W. Y., & Mabrouk, S. E. (2019). Importance of patient education in management of patients with rheumatoid arthritis: an intervention study. Egyptian Rheumatology and Rehabilitation, 46(1), 42–47. https://doi.org/10.4103/err.err_31_18
Siemons, L., ten Klooster, P. M., Vonkeman, H. E., van Riel, P. L. C. M., Glas, C. A. W., & van de Laar, M. A. F. J. (2014). How age and sex affect the erythrocyte sedimentation rate and C-reactive protein in early rheumatoid arthritis. BMC Musculoskeletal Disorders, 15(1), 368. https://doi.org/10.1186/1471-2474-15-368
Verhoeven, F., Tordi, N., Prati, C., Demougeot, C., Mougin, F., & Wendling, D. (2016). Physical activity in patients with rheumatoid arthritis. Joint Bone Spine, 83(3), 265–270. https://doi.org/https://doi.org/10.1016/j.jbspin.2015.10.002
Williamson, E., McConkey, C., Heine, P., Dosanjh, S., Williams, M., & Lamb, S. E. (2017). Hand exercises for patients with rheumatoid arthritis: an extended follow-up of the SARAH randomised controlled trial. BMJ Open, 7(4), e013121. https://doi.org/10.1136/bmjopen-2016-013121
Ye, H., Weng, H., Xu, Y., Wang, L., Wang, Q., & Xu, G. (2022). Effectiveness and safety of aerobic exercise for rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trials. BMC Sports Science, Medicine and Rehabilitation, 14(1), 17. https://doi.org/10.1186/s13102-022-00408-2
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